Monday, November 29, 1999

Drug industry financing tilts study in its favour

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London, May 10 (IANS) Drug studies financed by pharmaceutical companies frequently show positive results in favour of the sponsor, says recent research.A research group headed by the chairman of the Drug Commission of the German Medical Association, professor Wolf-Dieter Ludwig, describes the influence of sponsoring on the results, protocol and quality of drugs studies.The authors conclude that pharmaceutical companies exploit a wide variety of possibilities of manipulating study results.Apart from financing the study, financial links to the authors, such as payments for lectures, may tend to make the results of the study more favourable for the company.Not only the results themselves, but also their interpretation are significantly more often in accordance with the wishes of the sponsor.In some publications, the authors detected evidence that sponsors from the pharmaceutical industry had influenced study protocols.For example, placebos (substances that are made to resemble drugs but do not contain an active drug) were more frequently used in drug studies than was the case with independently financed studies.On the other hand, some favourable effects were linked to financial support from the pharmaceutical industry, says a release of Deutsches Arzteblatt International.The methodological quality of studies with industrial support tended to be better than with independent drug studies.These findings were published in Deutsches Arzteblatt International.

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